Some of these patients previously experienced angioedema with other drugs, including ACE inhibitors. Diovan should not be re-administered to patients who have had angioedema. Discontinuations due to renal dysfunction occurred in 1.1% of valsartan-treated patients and 0.8% of captopriltreated patients. The table shows the percentage buy diovan 160 mg without prescription of patients discontinued in the valsartan and captopril-treated groups in the VALsartan In Acute myocardial iNfarcTion trial with a rate of at least 0.5% in either of the treatment groups. The antihypertensive effect is substantially present within 2 weeks and maximal reduction is generally attained after 4 weeks.